Cas9 function and host genome sampling in Type II-A CRISPR–Cas adaptation
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چکیده
منابع مشابه
Cas9 function and host genome sampling in Type II-A CRISPR-Cas adaptation.
To acquire the ability to recognize and destroy virus and plasmid invaders, prokaryotic CRISPR-Cas systems capture fragments of DNA within the host CRISPR locus. Our results indicate that the process of adaptation by a Type II-A CRISPR-Cas system in Streptococcus thermophilus requires Cas1, Cas2, and Csn2. Surprisingly, we found that Cas9, previously identified as the nuclease responsible for u...
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The effect of nursing care plan based on “Roy Adaptation model” on psychological adaptation in patients with diabetes type II
Background: Applying “Roy Adaptation Model" in caring of patients with diabetes needs a context based planning using the principles of this model. But no study has been done up to now in Iranian nursing context Aim: To examine the effect of employing a care plan based on the Roy Adaptation Model on psychological adaptation in patient with type II diabetes. Methods: This clinical trial was perfo...
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CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) is a prokaryotic adaptable immune mechanism used by many bacteria and archaea to protect themselves from foreign nucleic acids. This complex system can recognize and cut non-self DNA in order to provide the prokaryotic organisms a strong defense against foreign viral or plasmid attacks and make the cell immune from further assau...
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The baculovirus-insect cell system (BICS) has been widely used to produce many different recombinant proteins for basic research and is being used to produce several biologics approved for use in human or veterinary medicine. Early BICS were technically complex and constrained by the relatively primordial nature of insect cell protein glycosylation pathways. Since then, recombination has been u...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 2015
ISSN: 0890-9369,1549-5477
DOI: 10.1101/gad.257550.114